Publications

Choroideremia: The Endpoint Endgame
Choroideremia is an X-linked retinal degeneration resulting from the progressive, centripetal loss of photoreceptors and …
Microperimetry as an Outcome Measure in RPGR-associated Retinitis Pigmentosa Clinical Trials
Purpose: To explore which microperimetry sensitivity index (pointwise sensitivity, mean sensitivity, and volume sensitivity) is …
Microperimetry Reliability Assessed From Fixation Performance
Microperimetry reliability should be assessed using fixation performance as summarized by BCEA95 rather than the level of fixation losses.
Code DOI
Microperimetry Reliability Assessed From Fixation Performance
A cross-sectional study to assess the clinical utility of modern visual function assessments in patients with inherited retinal disease: a mixed methods observational study protocol
Background: Treatment options for patients with inherited retinal disease are limited, although research into novel therapies is …
A Network Meta-Analysis of Retreatment Rates following Bevacizumab, Ranibizumab, Aflibercept and Laser for Retinopathy of Prematurity
Topic: To compare bevacizumab, ranibizumab, aflibercept, and laser treatment as primary therapies for retinopathy of prematurity (ROP) …
A Network Meta-Analysis of Retreatment Rates following Bevacizumab, Ranibizumab, Aflibercept and Laser for Retinopathy of Prematurity
Characterizing Visual Fields in RPGR Related Retinitis Pigmentosa Using Octopus Static-Automated Perimetry
Peripheral visual fields have not been as well defined by static automated perimetry as kinetic perimetry in RPGR-related retinitis …
Structural and Functional Characteristics of Color Vision Changes in Choroideremia
Color vision is considered a marker of cone function and its assessment in patients with retinal pathology is complementary to the …
Scotopic microperimetry: evolution, applications and future directions
For many inherited and acquired retinal diseases, reduced night vision is a primary symptom. Despite this, the clinical testing options …
Microperimetry Hill of Vision and Volumetric Measures of Retinal Sensitivity
As microperimetry has become an outcome measure in several gene-therapy clinical trials, three-dimensional visualization and volumetric sensitivity enables a complementary analysis of baseline disease characteristics and subsequent response to treatment, both as a signal of safety and efficacy.
Code DOI
Microperimetry Hill of Vision and Volumetric Measures of Retinal Sensitivity
Low luminance visual acuity as a clinical measure and clinical trial outcome measure: a scoping review
Purpose: The measurement of standard visual acuity (VA) is the most well-known part of any ophthalmic examination to indicate visual …
Low Luminance Visual Acuity and Low Luminance Deficit in Choroideremia and RPGR-Associated Retinitis Pigmentosa
Introduction: Choroideremia and RPGR-associated retinitis pigmentosa (RP) are two distinct inherited rod-cone degenerations, where good …
Clinical applications of microperimetry in RPGR -related retinitis pigmentosa: a review
Microperimetry, or fundus-tracked perimetry, is a precise static-automated perimetric technique to assess central retinal function. As …
Constraints on the power spectrum of primordial perturbations from small-scale structure
In this thesis the Big Bang and inflation theory are reviewed. The success of inflation is largely due to the predicted generation of …
Gamma rays from ultracompact minihalos: Potential constraints on the primordial curvature perturbation
Ultracompact minihalos (UCMHs) are dense dark matter structures, which can form from large density perturbations shortly after …
Constraints from primordial black hole formation at the end of inflation
Primordial black hole (PBH) abundance limits constrain the primordial power spectrum, and hence models of inflation, on scales far …
Generalized constraints on the curvature perturbation from primordial black holes
Primordial black holes (PBHs) can form in the early Universe via the collapse of large density perturbations. There are tight …