Microperimetry-based endpoints improved patient eligibility and detected treatment efficacy in a larger proportion of RPGR gene therapy trial participants than low luminance visual acuity.
Desktop app for plotting patient vision testing progress across visits for common ophthalmic functional measures.
Mesopic microperimetry was recommended as a stable and reliable outcome measure in inherited retinal disease, while scotopic microperimetry was limited by poorer reliability and floor effects in this cohort.
Statistical comparison of visual function measures and imaging biomarkers for inherited retinal disease trials.